Coincidental visualization of an atypical bronchial carcinoid on Tc-99m-sestamibi scan in Kallmann's syndrome

YAPAR Z., KIBAR M., SUKAN A., Paydas S., ZEREN H., INAL M. E.

ANNALS OF NUCLEAR MEDICINE, vol.16, no.1, pp.61-65, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 1
  • Publication Date: 2002
  • Doi Number: 10.1007/bf02995293
  • Journal Name: ANNALS OF NUCLEAR MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.61-65
  • Keywords: Tc-99m-sestamibi, carcinoid, Kallmann's syndrome, TC-99M MIBI, TUMOR, SCINTIGRAPHY, LOCALIZATION, ADENOMA, TL-201
  • Çukurova University Affiliated: Yes

Abstract

We report a case of an atypical bronchial carcinoid showing sestamibi uptake. A 27-year-old man with Kallmann's syndrome and hyperparathyroidism had parathyroid scintigraphy with Tc-99m-sestamibi. A focal uptake was observed on the right perihilar region, and this right perihilar mass was demonstrated on computed tomography and proved histologically to be an atypical bronchial carcinoid tumor. Factors which may explain the tumoral avidity for sestamibi are increased blood flow, transmembrane potentials of plasma and mitochondrial membranes and the relative number of mitochondria present in the cells of this carcinoid tumor. The importance of this case is the coincidence of an atypical carcinoid in a patient with significant failure of secondary sexual characteristics, right renal agenesis and bilateral anosmia associated with Kallmann's syndrome.