Evaluation of Polyphenolic Profile and Antibacterial Activity of Pome-granate Juice in Combination with Rifampin (R) against MDR-TB Clinical Isolates

ALMATAR M., VAR I., KAYAR B., EKER E., Kafkas E., ZARIFIKHOSROSHAHI M., ...More

CURRENT PHARMACEUTICAL BIOTECHNOLOGY, vol.20, no.4, pp.317-326, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 4
  • Publication Date: 2019
  • Doi Number: 10.2174/1389201020666190308130343
  • Journal Name: CURRENT PHARMACEUTICAL BIOTECHNOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.317-326
  • Keywords: Fresh Pomegranate Juice (FPJ), tuberculosis, synergistic effect, antimicrobial activity, new anti-tuberculosis drugs, MIC, MYCOBACTERIUM-TUBERCULOSIS, POMEGRANATE JUICE, PYRAZINAMIDE, INFLAMMATION, PREVENTION, TANNINS, GROWTH, DRUGS, L.
  • Çukurova University Affiliated: Yes

Abstract

Background: The global rise of multi-drug resistant M. tuberculosis demands unconventional treatment to enhance the efficiency of current drugs. Punica granatum, which is known as pomegranate, is considered as a member of the Punicaceae family. Pomegranate, which is broadly documented for its activity against a wide spectrum of bacterial pathogens, deserves further scrutiny in this respect.