Peripheral neurotoxic effects of cisplatin on rats and treatment with rutin

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YAŞAR H., ERSOY A., Cimen F. K., MAMMADOV R., KURT N., Arslan Y. K.

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, cilt.28, sa.11, ss.1537-1543, 2019 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 11
  • Basım Tarihi: 2019
  • Doi Numarası: 10.17219/acem/111819
  • Dergi Adı: ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1537-1543
  • Anahtar Kelimeler: apoptosis, antioxidants, cisplatin, rutin, caspase-3, OXIDATIVE STRESS, APOPTOSIS, PROTECTS, DEFICITS, ASSAY
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Çukurova Üniversitesi Adresli: Hayır

Özet

Background. Cisplatin, used in cancer treatment, has toxic and apoptotic effects on the peripheral nervous system. Rutin, also known as vitamin P, has antioxidant and antiapoptotic activity.