Development of Biodegradable and Biobased Poly(glycerol levulinate-co-glycerol malonate) Copolyesters with Controlled Degradation

Gulec H. R., Kareem Z., Karaboyun M., EYİLER E.

Macromolecules, cilt.58, sa.18, ss.9952-9961, 2025 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 58 Sayı: 18
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1021/acs.macromol.5c00383
  • Dergi Adı: Macromolecules
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Biotechnology Research Abstracts, Chemical Abstracts Core, Chimica, Compendex, MEDLINE, Nature Index
  • Sayfa Sayıları: ss.9952-9961
  • Çukurova Üniversitesi Adresli: Evet

Özet

Fully biobased oligomers were synthesized from glycerol, levulinic acid, and malonic acid via melt polycondensation. Itaconic acid with a carbon–carbon double bond was incorporated to enable cross-linking using dicumyl peroxide. The effect of the monomer molar ratio on material properties was investigated to understand the structure–property relationships. The addition of malonic acid, acting as both a monomer and a secondary cross-linker, was found to tune the glass-transition temperature, thermal stability, and degradation behavior of the cross-linked random copolyesters. Thermogravimetric analysis (TGA) revealed that malonic acid significantly improved the thermal stability, increasing it by up to 7.6% compared to the neat polymer. The cross-linked copolyesters exhibited excellent degradation profiles, making them suitable for biomedical applications where controlled degradation is essential. Additionally, they demonstrated outstanding shape memory properties, with a nearly 100% shape recovery, offering further potential for biomedical device fabrication.