Effect of caffeic acid phenethyl ester on corneal neovascularization in rats

Totan Y., Aydın E., Çekiç O., Dağlioğlu M., Borazan M., Daglioglu K.

CURRENT EYE RESEARCH, cilt.23, sa.4, ss.291-297, 2001 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 4
  • Basım Tarihi: 2001
  • Doi Numarası: 10.1076/ceyr.23.4.291.5453
  • Dergi Adı: CURRENT EYE RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.291-297
  • Çukurova Üniversitesi Adresli: Evet

Özet

Purpose. Caffeic acid phenethyl ester (CAPE), a biologically active component of propolis from honeybee hives, has potent antiinflammatory and antioxidant properties. We aimed to evaluate the ability of topically applied CAPE in comparison with known steroidal (dexamethasone sodium phosphate) and nonsteroidal (indomethacin) topical agents to reduce corneal neovascularization (CNV) induced by silver nitrate cauterization in rats.