Relationship between interleukin-2 promoter polymorphism and preeclampsia

TURGUT O., Luleyap U., ERKOC M. A., PAZARCI P., AY G.

CUKUROVA MEDICAL JOURNAL, cilt.42, sa.4, ss.732-736, 2017 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42 Sayı: 4
  • Basım Tarihi: 2017
  • Doi Numarası: 10.17826/cutf.325742
  • Dergi Adı: CUKUROVA MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.732-736
  • Çukurova Üniversitesi Adresli: Evet

Özet

Purpose: One of the cytokines involved in the immune system is interleukin-2 (IL-2). It is contemplated that polymorphisms in the promoter region of the IL-2 gene may be one of the determining factors in the maternal immunization system associated with abnormal placentation resulting in preeclampsia. This study tried to determine the protective genotypes for preeclampsia by genotyping the -384 polymorphisms in the promoter region of interleukin 2 gene in preeclamptic Turkish women.