Relationship between interleukin-2 promoter polymorphism and preeclampsia


TURGUT O., Luleyap U., ERKOC M. A. , PAZARCI P. , AY G.

CUKUROVA MEDICAL JOURNAL, vol.42, no.4, pp.732-736, 2017 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 4
  • Publication Date: 2017
  • Doi Number: 10.17826/cutf.325742
  • Title of Journal : CUKUROVA MEDICAL JOURNAL
  • Page Numbers: pp.732-736

Abstract

Purpose: One of the cytokines involved in the immune system is interleukin-2 (IL-2). It is contemplated that polymorphisms in the promoter region of the IL-2 gene may be one of the determining factors in the maternal immunization system associated with abnormal placentation resulting in preeclampsia. This study tried to determine the protective genotypes for preeclampsia by genotyping the -384 polymorphisms in the promoter region of interleukin 2 gene in preeclamptic Turkish women.