Prophylactic red blood cell exchange may be beneficial in the management of sickle cell disease in pregnancy


Asma S., Kozanoglu I., Tarim E., Sariturk C., Gereklioglu Ç. , Akdeniz A., ...Daha Fazla

TRANSFUSION, cilt.55, ss.36-44, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 55 Konu: 1
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1111/trf.12780
  • Dergi Adı: TRANSFUSION
  • Sayfa Sayıları: ss.36-44

Özet

BackgroundSickle cell disease (SCD) is associated with chronic hemolysis and painful episodes. Pregnancy accelerates sickle cell complications, including prepartum and postpartum vasoocclusive crisis, pulmonary complications, and preeclampsia or eclampsia. Fetal complications include preterm birth and its associated risks, intrauterine growth restriction, and a high rate of perinatal mortality. The purpose of this study was to evaluate pregnancy outcomes in patients with SCD who underwent planned preventive red blood cell exchange (RBCX).