Synthesis of heterocycles via sequential Pd/Ru-catalysed allene insertion-nucleophile incorporation-olefin metathesis

DÖNDAŞ H. A., Balme G., Blandine C., Grigg R., Hodgeson A., Morris J., ...Daha Fazla

TETRAHEDRON LETTERS, cilt.42, sa.49, ss.8673-8675, 2001 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42 Sayı: 49
  • Basım Tarihi: 2001
  • Doi Numarası: 10.1016/s0040-4039(01)01810-x
  • Dergi Adı: TETRAHEDRON LETTERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.8673-8675
  • Çukurova Üniversitesi Adresli: Hayır

Özet

A novel sequential palladium/ruthenium-catalysed three-component process is described involving allenylation of aryl/heteroaryl iodides to generate (pi -allyl) palladium species which are intercepted by nitrogen nucleophiles to afford 1,6- and 1,7-dienes. Subsequent ring-closing metathesis affords N-heterocycles in good yield. (C) 2001 Elsevier Science Ltd. All rights reserved.