Catheter-directed thrombolysis of acute deep vein thrombosis in the lower extremity of a child with interrupted inferior vena cava

Oguzkurt L., Ozkan U., Tercan F., Koc Z.

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, vol.30, no.2, pp.332-334, 2007 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 2
  • Publication Date: 2007
  • Doi Number: 10.1007/s00270-005-0337-0
  • Page Numbers: pp.332-334


We present the case of a 14-year-old girl who developed acute deep vein thrombosis (DVT) in her right lower extremity. Laboratory testing revealed protein S deficiency, and the patient's father also had this abnormality with a history of lower extremity DVT. Manual thromboaspiration followed by catheter-directed thrombolysis resulted in total clearance of all thrombi. Computed tomography and later venography revealed an interrupted inferior vena cava. Catheter-directed thrombolysis is an established treatment for adults with acute DVT. To the best of our knowledge, this report is the first to describe catheter-directed thrombolysis in a pediatric patient with lower extremity DVT. Our results suggest that catheter-directed thrombolysis is safe and effective for use in selected older children and adolescents with acute DVT in the lower extremity.