Granulocytic sarcoma of the heart: Extramedullary relapse of acute myeloblastic leukemia after allogeneic stem cell transplantation successfully treated by chemotherapy alone

Kara I., Sahin B., Paydas S., Kara B.

LEUKEMIA & LYMPHOMA, cilt.46, sa.7, ss.1081-1084, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 7
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1080/10428190500057700
  • Dergi Adı: LEUKEMIA & LYMPHOMA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1081-1084
  • Anahtar Kelimeler: AML, granulocytic sarcoma of the heart, extramedullary relapse, post-transplant, BONE-MARROW-TRANSPLANTATION, MYELOID-LEUKEMIA, TUMORS, CHLOROMA, AUTOPSY
  • Çukurova Üniversitesi Adresli: Evet

Özet

We present a case of granulocytic sarcoma (GS) of the heart. A 28-year-old man with relapsed acute myelogenous leukemia (AML-M2) had undergone a non-myeloablative allogeneic peripheral stem cell transplantation. Three years following transplantation, masses were evidenced in his heart by echocardiography but had completely disappeared following a common chemotherapy etoposide, mitoxantrone, ara-C (EMA) regimen for relapsed AML. The involvement of the heart with GS is very rare and this is the first case of extramedullary disease in the heart after allogeneic transplantation. Here we present the case history and related literature has been reviewed.