Atıf İçin Kopyala
Güven U. M., Yenilmez E.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, cilt.51, ss.506-512, 2019 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
51
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Basım Tarihi:
2019
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Doi Numarası:
10.1016/j.jddst.2019.03.016
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Dergi Adı:
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.506-512
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Anahtar Kelimeler:
Olopatadine hydrochloride, Nanoparticles, Ocular application, Drug delivery system, Sustained release, POLYMERIC NANOPARTICLES, DRUG-RELEASE, CHITOSAN NANOPARTICLES, CELLULAR UPTAKE, PART II, SYSTEMS, TEAR, EYE, FABRICATION, ADSORPTION
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Çukurova Üniversitesi Adresli:
Evet
Özet
Introduction: Allergic eye diseases includes a spectrum of diseases, with each state being characterized by a complicated immunopathology. In the present study, polymeric Kollidon (R) SR nanoparticles loaded with olopatadine hydrochloride (OLO) were formulated as a suspension for ocular drug delivery. The formulations were developed to treat ocular allergic disease and characterized by their improved duration of corneal retention.