Protective effect of L-arginine on gentamicin-induced nephrotoxicity in rats


Bashan B., Bashan P., SEÇİLMİŞ M. A. , ŞİNGİRİK E.

INDIAN JOURNAL OF PHARMACOLOGY, cilt.46, ss.608-612, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 46 Konu: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.4103/0253-7613.144915
  • Dergi Adı: INDIAN JOURNAL OF PHARMACOLOGY
  • Sayfa Sayısı: ss.608-612

Özet

Introduction: L-arginine has a protective effect on gentamicin-induced renal failure and it may decrease the tubular reabsorption of another cationic substance, gentamicin due to its cationic structure. The aim of this study is to compare the possible protective effects of L-arginine and its inactive isomer D-arginine on gentamicin-induced nephrotoxicity in rats.