Protective effect of L-arginine on gentamicin-induced nephrotoxicity in rats


Bashan B., Bashan P., SEÇİLMİŞ M. A. , ŞİNGİRİK E.

INDIAN JOURNAL OF PHARMACOLOGY, vol.46, no.6, pp.608-612, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 6
  • Publication Date: 2014
  • Doi Number: 10.4103/0253-7613.144915
  • Title of Journal : INDIAN JOURNAL OF PHARMACOLOGY
  • Page Numbers: pp.608-612

Abstract

Introduction: L-arginine has a protective effect on gentamicin-induced renal failure and it may decrease the tubular reabsorption of another cationic substance, gentamicin due to its cationic structure. The aim of this study is to compare the possible protective effects of L-arginine and its inactive isomer D-arginine on gentamicin-induced nephrotoxicity in rats.