Testicular mixed germ cell tumor with polyembryoma component in brothers

Bakaris S., Resim S., Tunali N.

PEDIATRIC AND DEVELOPMENTAL PATHOLOGY, cilt.8, ss.92-97, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 8 Konu: 1
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1007/s10024-004-2123-4
  • Sayfa Sayıları: ss.92-97


We report the case of a 17-year-old male with a testicular tumor and high serum levels of alpha-fetoprotein. The patient was treated with surgery followed by combination chemotherapy with bleomycin, etoposide, and cisplatin. Histologic examination showed features of a mixed germ cell tumor composed of mature teratoma, immature teratoma, embryonal carcinoma, yolk sac tumor, and polyembryoma. He is currently well, and his serum levels of alpha-fetoprotein have been normal more than 5 months after treatment. His brother, aged 17 years at the time, had a similar tumor removed from the right testicle 5 years previously.