Effects of Copper Oxide Nanoparticles on Antioxidant Enzyme Activities and on Tissue Accumulation of Oreochromis niloticus


Tuncsoy M., DURAN S., Ay O., Cicik B., ERDEM C.

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, cilt.99, sa.3, ss.360-364, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 99 Sayı: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1007/s00128-017-2129-z
  • Dergi Adı: BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.360-364
  • Anahtar Kelimeler: Copper oxide nanoparticles, Accumulation, Antioxidant enzyme, Oreochromis niloticus, MYTILUS-GALLOPROVINCIALIS, OXIDATIVE STRESS, EXPOSURE, BIOAVAILABILITY, BIOMARKERS, TOXICITY, SULFATE, METALS, LIVER, GILL
  • Çukurova Üniversitesi Adresli: Evet

Özet

Accumulation of copper oxide nanoparticles (CuO NPs) in gill, liver and muscle tissues of Oreochromis niloticus and its effects on superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) activities in gill and liver tissues were studied after exposing the fish to 20 A mu g/L Cu over 15 days. Copper levels and enzyme activities in tissues were determined using spectrophotometric (ICP-AES and UV) techniques respectively. No mortality was observed during the experiments. Copper levels increased in gill and liver tissues of O. niloticus compared to control when exposed to CuO NPs whereas exposure to metal had no effect on muscle level at the end of the exposure period. Highest accumulation of copper was observed in liver while no accumulation was detected in muscle tissue. SOD, CAT activities decreased and GPx activity increased in gill and liver tissues when exposed to CuO NPs.