Immunohistochemical Study of Cyclooxygenase-2 Expression in Prostate Carcinoma: It's Relation with Apoptosis and Angiogenesis


BAĞIR KILIÇ E., AÇIKALIN A., İZOL V., SEYDAOĞLU G., ERDOĞAN Ş.

UROONKOLOJI BULTENI-BULLETIN OF UROONCOLOGY, vol.15, no.4, pp.144-147, 2016 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 4
  • Publication Date: 2016
  • Doi Number: 10.4274/uob.708
  • Journal Name: UROONKOLOJI BULTENI-BULLETIN OF UROONCOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.144-147
  • Çukurova University Affiliated: Yes

Abstract

Objective: Prostate carcinoma (PC) is one of the most commonly diagnosed cancer types with significant rates of mortality and morbidity. The etiology of PC is not clear. Cytokine and mediators at the inflammatory pathway plays role at the various steps of the relation between chronic inflammation and cancer. The objective of this study is to determine if there is relationship between cyclooxygenase-2 (COX) apoptosis and angiogenesis in patients with PC.