Akademik Veri Yönetim Sistemi
Industrial Crops and Products, cilt.226, 2025 (SCI-Expanded)
Lavandula L. species are highly regarded for their cosmetic, culinary, and medicinal uses. The essential oil of Lavandula angustifolia Mill. has been recognised worldwide for its sedative, antidepressant, antiseptic, antifungal, relaxing and antiemetic properties, as well as its low toxicity risk. The aim of this research was to investigate the chemical constituents and antibacterial efficacy of microemulsion and microemulgel forms of the flowers of L. angustifolia. Formulations of microemulsions and microemulgels were prepared using the essential oils of L. angustifolia performing the globule size, zeta potential, pH, viscosity, rheology, spreadability, and texture profile to evaluate the characteristics of the formulations. Pseudoternary phase diagrams were constructed for formulations comprising an oil, mixed surfactant, and water emulsion system along with an additional quaternary component. Microemulsions were transformed into microemulgels using Carbopol 940 polymer. The antibacterial properties of these essential oils and formulations were tested against Staphylococcus aureus, E. coli, Pseudomonas aeruginosa, Streptococcus agalactiae, and Enterococcus faecalis using the broth dilution method. Gas chromatography-mass spectrometry identified 27 primary components, which were linalool, linalyl acetate, trans-β-ocimene, terpinen-4-ol, and α-terpineol, as the major constituents of the essential oils. As a result, both the essential oils and their formulations showed antibacterial activity against all tested bacterial strains. These findings indicated that L. angustifolia essential oils and formulations could be used as natural resources to develop novel and effective antibacterial agents in the food, cosmetics and healthcare sectors.