Ochronotic Involvement of the Aortic and Mitral Valves in a 72-Year-Old Man


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ATALAY A., GÖÇEN U. , BAŞTÜRK Y., Kozanoglu E. , YALINIZ H.

TEXAS HEART INSTITUTE JOURNAL, cilt.42, ss.84-86, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 42 Konu: 1
  • Basım Tarihi: 2015
  • Doi Numarası: 10.14503/thij-14-4138
  • Dergi Adı: TEXAS HEART INSTITUTE JOURNAL
  • Sayfa Sayıları: ss.84-86

Özet

Ochronosis, an autosomal recessive metabolic disorder, causes an excess of homogentisic acid that results in adverse pigmentation, calcification, and inflammation of cartilaginous and other tissues. Cardiovascular abnormalities are less frequently reported than are other manifestations. In rare cases, ochronosis can cause valvular heart disease. We report the case of a 72-year-old man with aortic stenosis and mitral insufficiency who was diagnosed with ochronosis while undergoing surgical aortic and mitral valve replacement. We discuss the history and surgical management of alkaptonuric ochronosis.