Bone Tissue Bioprinting for Craniofacial Reconstruction

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DATTA P., Ozbolat V., AYAN B., DHAWAN A., OZBOLAT I. T.

BIOTECHNOLOGY AND BIOENGINEERING, cilt.114, sa.11, ss.2424-2431, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 114 Sayı: 11
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1002/bit.26349
  • Dergi Adı: BIOTECHNOLOGY AND BIOENGINEERING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2424-2431
  • Anahtar Kelimeler: craniofacial tissue, bioprinting, bone repair, regenerative medicine, MESENCHYMAL STEM-CELLS, BIOREACTOR SYSTEMS, HYDROGEL, FABRICATION, CONSTRUCTS, SCAFFOLDS
  • Çukurova Üniversitesi Adresli: Evet

Özet

Craniofacial (CF) tissue is an architecturally complex tissue consisting of both bone and soft tissues with significant patient specific variations. Conditions of congenital abnormalities, tumor resection surgeries, and traumatic injuries of the CF skeleton can result in major deficits of bone tissue. Despite advances in surgical reconstruction techniques, management of CF osseous deficits remains a challenge. Due its inherent versatility, bioprinting offers a promising solution to address these issues. In this review, we present and analyze the current state of bioprinting of bone tissue and highlight how these techniques may be adapted to serve regenerative therapies for CF applications. (C) 2017 Wiley Periodicals, Inc.