Bone Tissue Bioprinting for Craniofacial Reconstruction


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DATTA P., Ozbolat V. , AYAN B., DHAWAN A., OZBOLAT I. T.

BIOTECHNOLOGY AND BIOENGINEERING, vol.114, no.11, pp.2424-2431, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 114 Issue: 11
  • Publication Date: 2017
  • Doi Number: 10.1002/bit.26349
  • Title of Journal : BIOTECHNOLOGY AND BIOENGINEERING
  • Page Numbers: pp.2424-2431

Abstract

Craniofacial (CF) tissue is an architecturally complex tissue consisting of both bone and soft tissues with significant patient specific variations. Conditions of congenital abnormalities, tumor resection surgeries, and traumatic injuries of the CF skeleton can result in major deficits of bone tissue. Despite advances in surgical reconstruction techniques, management of CF osseous deficits remains a challenge. Due its inherent versatility, bioprinting offers a promising solution to address these issues. In this review, we present and analyze the current state of bioprinting of bone tissue and highlight how these techniques may be adapted to serve regenerative therapies for CF applications. (C) 2017 Wiley Periodicals, Inc.