Volatile profile, in silico toxicity prediction, and antioxidant and antimicrobial activities of Laurus nobilis L. essential oil from distinct geographical locations


Tahiri N. E. H., Soulo N., El Ghouizi A., Saghrouchni H., El Khomsi M., Ousaaid D., ...More

Chemical Review and Letters, vol.7, no.10, pp.884-894, 2024 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 10
  • Publication Date: 2024
  • Doi Number: 10.22034/crl.2024.445481.1300
  • Journal Name: Chemical Review and Letters
  • Journal Indexes: Scopus
  • Page Numbers: pp.884-894
  • Keywords: Antibacterial effect, Antioxidant activity, Laurus nobilis, Polyphenolic compounds
  • Çukurova University Affiliated: Yes

Abstract

Laurus nobilis L. is one of the most interesting medicinal plants for treating different diseases. The present study was undertaken to determine the volatile profile and biological properties of Laurus nobilis L. collected from different Moroccan geographical zones. The plants investigated contained considerable amounts of antioxidants. The phytochemistry analysis showed a high variability of bioactive compounds found in both samples under study with abundance of eucalyptol (39.12%), α-terpinyl acetate (15.83%), methyleugenol (7.77%), and α-terpineol (4.74%) for sample collected from Sfrou, whereas (1R,4aR,7R,8aR)-7-(2-hydroxypropan-2-yl) (18.62%), and methyleugenol (15.84%) were the major components detected from sample originated from Akchour and did not possess hepatotoxicity, cytotoxicity, and carcinogenicity. Staphylococcus aureus was the most sensitive bacteria and registered a diameter of inhibition of 30 mm for EO from Akchour and 25 from Sefrou with a minimal inhibitory concentration (MIC) of 1/640. Both samples under study showed moderate antifungal activity against C. albicans and S. cerevisiae.