Huge bilateral pulmonary and pleural metastasis from intracranial meningioma: a case report and review of the literature

Erman T. , Hanta I., Haciyakupoglu S., Zorludemir S., Zeren H., Gocer A.

JOURNAL OF NEURO-ONCOLOGY, cilt.74, sa.2, ss.179-181, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 74 Konu: 2
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1007/s11060-004-3014-2
  • Sayfa Sayıları: ss.179-181


A case of recurrent meningioma with atypical features and extracranial metastases is reported. A 34-year-old female was operated in 1996, 2000, and 2002, and frontal parasagital meningioma was extirpated. Histological diagnoses of all the resected tumors were meningotheliomatous meningioma, WHO Grade I. However, 2 years later, the tumor recurred in the frontal scalp and was removed again totally. Histological diagnosis was reported as an atypical meningioma; meningotheliomatous type; WHO Grade II. She received radiation therapy. But the tumor had metastasized to the lung and pleura. Transthoracic tru-cut biopsy was performed from large mass of the left lung. Cytopathology was consistent with malignant meningioma, metastasis from the patient's known intracranial meningioma. Ki-67 staining index at the primary and metastatic sites of the present cases were 7 and 5%, respectively. We reviewed and discussed the histopathological features and mechanisms of metastasizing meningioma.