The antibacterial effect of bee venom on subclinical mastitis agents: an alternative for local treatment


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Güven Gökmen T., Yazgan H., Sevin S., Turut N., Karahan Ş., Eşki F., ...Daha Fazla

JOURNAL OF APPLIED ANIMAL RESEARCH, cilt.51, sa.1, ss.323-332, 2023 (SCI-Expanded)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 51 Sayı: 1
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1080/09712119.2023.2197477
  • Dergi Adı: JOURNAL OF APPLIED ANIMAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, Food Science & Technology Abstracts, Veterinary Science Database, Directory of Open Access Journals
  • Sayfa Sayıları: ss.323-332
  • Çukurova Üniversitesi Adresli: Evet

Özet

Subclinical mastitis is an important problem in terms of the dairy economy all over the world and due to

the increasing antibiotic resistance day by day, there is a great need for new antibiotic alternatives and

natural products. The aim of this study is to examine the effectiveness of bee venom against bacterial

mastitis agents. Methods, such as well diffusion, disc diffusion, microdilution and time-kill analyses,

were applied to 12 bacteria species isolated from milk samples. Effective results were obtained in

microdilution and time-kill analysis. MIC values were determined in the range of 12.550 µg/ml and

time-kill times were observed in the range of 124 h. In addition, bacterial suspensions from 12

species were prepared and there were effective against mixed infection in vitro. As a result, bee

venom, as an antibiotic alternative, can give satisfactory results in the treatment of subclinical mastitis

and mixed infections. Field studies and treatment trials should be emphasized.