beta-Globin chain abnormalities with coexisting alpha-thalassemia mutations

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GÜVENÇ B., Canataroglu A., Unsal C., Yildiz Ş. S., Turhan F. T., Bozdogan S. T., ...More

ARCHIVES OF MEDICAL SCIENCE, vol.8, no.4, pp.644-649, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 4
  • Publication Date: 2012
  • Doi Number: 10.5114/aoms.2012.28723
  • Journal Name: ARCHIVES OF MEDICAL SCIENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.644-649
  • Çukurova University Affiliated: Yes

Abstract

Introduction: The frequency of hemoglobinopathies is still high in Adana, the biggest city of the Cukurova Region that is located in the southern part of Turkey. Our aim was to identify the concomitant mutations in alpha- and beta-globin genes which lead to complex hemoglobinopathies and to establish an appropriate plan of action for each subject, particularly when prenatal diagnosis is necessary.