The genotoxic and antigenotoxic effects of Aloe vera leaf extract in vivo and in vitro


Kayraldiz A., Kocaman A. Y., Rencuzogullari E., Istifli E. S., İLA H. B., TOPAKTAŞ M., ...More

TURKISH JOURNAL OF BIOLOGY, vol.34, no.3, pp.235-246, 2010 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 3
  • Publication Date: 2010
  • Doi Number: 10.3906/biy-0812-27
  • Journal Name: TURKISH JOURNAL OF BIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.235-246
  • Keywords: Aloe vera, culture of human lymphocytes in vitro, bone marrow cells, rat, Salmonella typhimurium, CHROMOSOMAL-ABERRATIONS, EMODIN, CYTOTOXICITY, INHIBITION, MECHANISM, CELLS, ANTHRAQUINONES, CHRYSOPHANOL, MUTAGENICITY, PESTICIDES
  • Çukurova University Affiliated: Yes

Abstract

The genotoxic and antigenotoxic effects of Aloe vera leaf extract (AV) were investigated using the chromosome aberrations (CAs) test for the bone marrow cells of rats, sister chromatid exchanges (SCEs) and micronucleus (MN) and CAs tests for human lymphocytes, and the Ames Salmonella/microsome test system.