Role of KIR genes and genotypes in susceptibility to or protection against hepatitis B virus infection in a Turkish cohort


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KİBAR F. , Ozturk O. G. , ULU A. , ERKEN E. , Inal S. , DİNKÇİ S. , et al.

MEDICAL SCIENCE MONITOR, cilt.20, ss.28-34, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 20
  • Basım Tarihi: 2014
  • Doi Numarası: 10.12659/msm.889893
  • Dergi Adı: MEDICAL SCIENCE MONITOR
  • Sayfa Sayısı: ss.28-34

Özet

Background: Killer cell immunoglobulin-like receptors (KIRs) are a family of inhibitory and activating receptors expressed by natural killer (NK) cells and regulate NK cell activity in the innate response against viral infections. The aim of this study was to determine the possibility of KIR genes and genotypes as a candidate for susceptibility to or protection against chronic hepatitis B virus (HBV) infection or spontaneous remission of the infection in a Turkish cohort.