Comparison of single-dose and repeated levosimendan infusion in patients with acute exacerbation of advanced heart failure

Tasal, Abdurrahman; DEMİR, MESUT; KANADAŞI, MEHMET; BACAKSIZ, AHMET; Vatankulu, Mehmet; Sahin, Durmus; Eker, Rabia; BOZKURT, ABDİ; Acarturk, Esmeray

doi:10.12659/msm.889767

Comparison of single-dose and repeated levosimendan infusion in patients with acute exacerbation of advanced heart failure

Tasal A., DEMİR M., KANADAŞI M., BACAKSIZ A., Vatankulu M. A., Sahin D. Y., ...Daha Fazla

MEDICAL SCIENCE MONITOR, cilt.20, 2014 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 20
Basım Tarihi: 2014
Doi Numarası: 10.12659/msm.889767
Dergi Adı: MEDICAL SCIENCE MONITOR
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Çukurova Üniversitesi Adresli: Evet

Özet

Background: Levosimendan (LS) is a novel inodilator that improves cardiac performance, central hemodynamics, and symptoms of patients with decompensated chronic heart failure. The aim of this study was to compare the effects of single and repeated LS infusion on left ventricular performance, biomarkers, and neurohormonal activation in patients with acute heart failure.