Effects of pycnogenol on ischemia/reperfusion-induced inflammatory and oxidative brain injury in rats

Ozoner B., Yuceli S., Aydin S., YAZICI G. N., SUNAR M., Arslan Y. K., ...Daha Fazla

NEUROSCIENCE LETTERS, cilt.704, ss.169-175, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 704
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.neulet.2019.04.010
  • Dergi Adı: NEUROSCIENCE LETTERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.169-175
  • Anahtar Kelimeler: Ischemia/reperfusion, Brain injury, Rycnogenol, Antioxidant, Anti-inflammatory, TUMOR-NECROSIS-FACTOR, PINUS-MARITIMA BARK, REPERFUSION INJURY, ANTIOXIDANT ACTIVITY, CEREBRAL-ISCHEMIA, FREE-RADICALS, GLUTATHIONE, EXTRACT, MALONDIALDEHYDE, MECHANISMS
  • Çukurova Üniversitesi Adresli: Hayır

Özet

Background: Ischemia/reperfusion (I/R) injury results from the onset of re-circulation following a perfusion deterioration period in the tissues, resulting in more damage than that caused by perfusion deterioration. This study aimed to determine the effects of pycnogenol on I/R injury in rat brain tissues.