Two Cu(II) complexes from an N-alkylated benzimidazole: synthesis, structural characterization, and biological properties

KÖSE M., DIĞRAK M., Gonul I., Mckee V.

JOURNAL OF COORDINATION CHEMISTRY, cilt.67, sa.10, ss.1746-1759, 2014 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 67 Sayı: 10
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1080/00958972.2014.920502
  • Dergi Adı: JOURNAL OF COORDINATION CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1746-1759
  • Çukurova Üniversitesi Adresli: Evet

Özet

Two mononuclear copper(II) complexes, [Cu(L)Cl-2](CH3OH)(2) and [Cu(L)(NO3)(2)], were prepared and characterized by spectroscopic and analytic methods, where L is 2,6-bis(1-butyl-1H-benzo[d] imidazol-2-yl) pyridine. Molecular structures of the complexes were determined by X-ray diffraction. The X-ray data revealed that the complexes are mononuclear and coordination geometry around Cu(II) is distorted square pyramidal. The complexes were screened for their in vitro antibacterial and antifungal activities. The complexes show moderate antifungal activities against Saccharomyces cerevisiae, Candida utilis, and Candida albicans. Moreover, the complexes inhibit the development of Escherichia coli and Klebsiella pneumoniae.