Intestinal ischemia-reperfusion induced diaphragm contractility dysfunction: Electrophysiological and ultrastructural study in a neonatal rat model

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TAŞKINLAR H., NAYCI A., ÇÖMELEKOĞLU Ü., POLAT G., ZORLUDEMİR S., Avlan D.

JOURNAL OF PEDIATRIC SURGERY, vol.51, no.3, pp.354-359, 2016 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 51 Issue: 3
• Publication Date: 2016
• Doi Number: 10.1016/j.jpedsurg.2015.08.013
• Journal Name: JOURNAL OF PEDIATRIC SURGERY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.354-359
• Çukurova University Affiliated: Yes

Abstract

Aim: To evaluate the remote effect of intestinal ischemia reperfusion (IR) injury mediated by tumor necrosis factor alpha (TNF-alpha) on diaphragm contractility functions and whether administration of NAC may counteract the possible detrimental effects in an experimental neonatal rat model.