The Possible Effects of Dapagliflozin on 12-derived Electrocardiogram in Patients with Type 2 Diabetes Mellitus

Akkus O., Akkus G., Kaypakli O.

ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, vol.19, no.2, pp.207-213, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.2174/1871530319666181218121508
  • Journal Name: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.207-213
  • Keywords: Type 2 diabetes mellitus, SGLT 2 inhibitor, electrolyte imbalance, 12-derived electrocardiogram, Tpe/QT, cardiovascular response, SGLT2 INHIBITORS, GLYCEMIC CONTROL, RISK
  • Çukurova University Affiliated: Yes

Abstract

Background: Dapagliflozin, sodium glucose cotransporter 2 inhibitor, has potential side effects on electrolyte imbalance as it has diuretic effects which include decreasing glucose reabsorption, increasing glucosuria and natriuresis. We aimed to determine the possible effects of dapagliflozin on electrocardiogram (ECG) in patients with type 2 DM.