Murata Vortex spinning (MVS) system is one of the unconventional systems for yarn manufacturing. It is suitable for spinning of 100% cotton fibers, synthetic fibers, and cotton/synthetic fiber blends which are 1 inch or more in length. The production ranges are between Ne 15-60. Vortex yarn and fabrics have low hairiness, clear appearance, high resistance to pilling and abrasion. In this study, the vortex yarns with Ne 30 are produced in different blend ratios in Murata Vortex Spinner using carded cotton, viscose, modal, silver-added polyester (Flexsil-D2), polyester, and nylon 6.6 fibers. Vortex spun yarns are tested to determine the yarn properties which are diameter, density, roundness (shape), unevenness, imperfection, Uster hairiness (H), Zweigle hairiness, tenacity, and elongation. The study reveals that the fiber type has quite significant effects on yarn properties. In terms of structural properties, cotton is the most negative fiber while regenerated cellulosic fibers are the most positive. As modal, nylon and polyester fiber increase yarn strength, nylon and viscose fiber increase breaking elongation. Viscose and modal reduce unevenness, imperfection and hairiness while polyester and nylon exhibit more negative effect on these properties.