Lhermitte-Duclos disease (dysplastic cerebellar gangliocytoma) - Review of the literature

Erman T., Yilmaz D. M., Tuna M., Zorludemir S., Ildan F., HACLYAKUPOGLU S.

NEUROSURGERY QUARTERLY, vol.17, no.2, pp.142-146, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 17 Issue: 2
  • Publication Date: 2007
  • Doi Number: 10.1097/wnq.0b013e318033a601
  • Journal Name: NEUROSURGERY QUARTERLY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.142-146
  • Çukurova University Affiliated: Yes

Abstract

Objectives: Lhermitte-Duclos disease (LDD), or dysplastic gangliocytoma of the cerebellum is a rare benign unilateral mass of the cerebellar cortex, characterized by a disarrangement of the normal cerebellar laminar cytoarchitecture and circumscribed enlargement of cerebellar folia. LDD was recently considered to be part of a multiple hamartoma-neoplasia syndrome [Cowden disease (CD)]. The debate whether LDD represents a neoplastic or hamartomatous lesion is still in progress.