Atıf İçin Kopyala
Grigg R., Kilner C., Sarker M. A. B., de la Cierva C. O., DÖNDAŞ H. A.
TETRAHEDRON, cilt.64, sa.37, ss.8974-8991, 2008 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
64
Sayı:
37
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Basım Tarihi:
2008
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Doi Numarası:
10.1016/j.tet.2008.05.132
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Dergi Adı:
TETRAHEDRON
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.8974-8991
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Anahtar Kelimeler:
metallo-azomethine ylides, cycloaddition, silver oxide, nitroolefins, pyrrolidines, spirocycles, AZA-CEPHALOTAXINE SKELETON, IN-SITU GENERATION, STEREOSELECTIVE PREPARATION, ANTIPSYCHOTIC AGENTS, ANALOGS, NITRO, STEREOCHEMISTRY, DERIVATIVES, DOPAMINE, SYSTEMS
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Çukurova Üniversitesi Adresli:
Hayır
Özet
13-Dipolar reactions of imines of both acyclic and cyclic alpha-amino esters with a range of nitroolefins using a combination of AgOAc or Ag(2)O with NEt(3) are described. In most cases the reactions were highly regio and stereospecific and endo-cycloadducts were obtained in good yield. However, in a few cases the initially formed cycloadducts underwent base catalysed epimerisation. The stereochemistry of the cycloadducts was assigned from NOE data and established unequivocally in several cases by X-ray crystallography. (C) 2008 Elsevier Ltd. All Fights reserved.