Inflammation-mediated fetal injury by maternal granulocyte-colony stimulating factor and high-dose intra-amniotic endotoxin in the caprine model

SEZİK, Mekin; KÖKER, AFŞİN; ÖZMEN, ÖZLEM; HALIGÜR, MEHMET; Kasikci, Duygu; AYDOĞAN, AHMET; ÖZATİK, ORHAN

doi:10.4274/tjod.tjod.galenos.2019.92300

Inflammation-mediated fetal injury by maternal granulocyte-colony stimulating factor and high-dose intra-amniotic endotoxin in the caprine model

SEZİK M., KÖKER A., ÖZMEN Ö., HALIGÜR M., Kasikci D., AYDOĞAN A., ...More

TURKISH JOURNAL OF OBSTETRICS AND GYNECOLOGY, vol.16, no.1, pp.41-49, 2019 (ESCI, Scopus, TRDizin)

Publication Type: Article / Article
Volume: 16 Issue: 1
Publication Date: 2019
Doi Number: 10.4274/tjod.tjod.galenos.2019.92300
Journal Name: TURKISH JOURNAL OF OBSTETRICS AND GYNECOLOGY
Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
Page Numbers: pp.41-49
Çukurova University Affiliated: Yes

Abstract

Objective: To define a novel experimental model with maternal intravenous (i.v.) granulocyte-colony stimulating factor (G-CSF) followed by a single- and high-dose of 20 mg intra-amniotic (IA) endotoxin to induce fetal brain injury in the preterm fetal goat.