A novel promoter controls Cyp19a1 gene expression in mouse adipose tissue


Creative Commons License

Zhao H., Innes J., Brooks D. C., Reierstad S., Yilmaz M. B., Lin Z., ...Daha Fazla

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, cilt.7, 2009 (SCI-Expanded) identifier identifier identifier

Özet

Background: Aromatase, the key enzyme in estrogen biosynthesis, is encoded by the Cyp19a1 gene. Thus far, 3 unique untranslated first exons associated with distinct promoters in the mouse Cyp19a1 gene have been described (brain, ovary, and testis-specific). It remains unknown whether aromatase is expressed in other mouse tissues via novel and tissue-specific promoters.