Virulence markers of opportunistic black yeast in Exophiala


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Sav H. , Ozakkas F., Altinbas R., Kiraz N., TUMGOR A., GUMRAL R., ...Daha Fazla

MYCOSES, cilt.59, ss.343-350, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 59 Konu: 6
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1111/myc.12478
  • Dergi Adı: MYCOSES
  • Sayfa Sayıları: ss.343-350

Özet

The black yeast genus Exophiala is known to cause a wide variety of diseases in severely ill individuals but can also affect immunocompetent individuals. Virulence markers and other physiological parameters were tested in eight clinical and 218 environmental strains, with a specific focus on human-dominated habitats for the latter. Urease and catalase were consistently present in all samples; four strains expressed proteinase and three strains expressed DNase, whereas none of the strains showed phospholipase, haemolysis, or co-haemolysis activities. Biofilm formation was identified in 30 (13.8%) of the environmental isolates, particularly in strains from dishwashers, and was noted in only two (25%) of the clinical strains. These results indicate that virulence factors are inconsistently present in the investigated Exophiala species, suggesting opportunism rather than pathogenicity.