Akademik Veri Yönetim Sistemi
Çukurova Anestezi ve Cerrahi Bilimler Dergisi, cilt.6, sa.1, ss.130-139, 2023 (Hakemli Dergi)
Aim: Since the first months of 2020, vaccination has become the most effective method to combat the COVID-19 pandemic. This study aims to describe the vaccination status of inpatients, the effectiveness of booster vaccine protocols, and the risk factors for intensive care unit (ICU) and mortality of COVID-19 patients. Methods: The study included 247 hospitalized patients in a tertiary care hospital due to COVID-19. Data of the participants were recorded using the hospital database and a questionnaire. Patients were divided into groups as mild-moderate-severe disease in terms of disease severity, ward and ICU in terms of hospitalization clinic. According to vaccination status, they were categorized as unvaccinated, Sinovac-based protocols, BioNTech-based protocols and others. Results: Of the 247 patients, 55.1% were male and the mean age was 60 ± 17.26 years. 38.5% of the patients were admitted to ICU and 9.3% died. It was observed that 38.8% of those admitted to ICU and 56.5% of those who died were not vaccinated. Being over 65 years (p=0.008), being hospitalized for over 7 days (p=0.003), having a severe illness (p=0.002), having a nervous system disease (p=0.005) and having other comorbidities (p=0.000) were significant risk factors for ICU admission, whereas disease severity (p=0.000) and comorbidities such as hypertension (p=0.000), diabetes mellitus (p=0.020) and cardiovascular diseases (p=0.000) were found to be risk factors for mortality. Vaccination generally decreased ICU admission and mortality, and rapel dose were found to reduce mortality, but the different was not statistically significant. Conclusions: Complete vaccination in COVID-19 is beneficial in preventing ICU admission and especially mortality.