Effects of Platelet-Rich Fibrin on Palatal Wound Healing After Free Gingival Graft Harvesting: A Comparative Randomized Controlled Clinical Trial


ÖZCAN M. , Ucak O. , ALKAYA B. , KEÇELİ S. , SEYDAOĞLU G. , HAYTAÇ M. C.

INTERNATIONAL JOURNAL OF PERIODONTICS & RESTORATIVE DENTISTRY, vol.37, no.5, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 5
  • Publication Date: 2017
  • Doi Number: 10.11607/prd.3226
  • Title of Journal : INTERNATIONAL JOURNAL OF PERIODONTICS & RESTORATIVE DENTISTRY

Abstract

This study was conducted to evaluate the effects of platelet-rich fibrin (PRF) on palatal wound healing after free gingival graft (FGG) harvesting. A total of 125 patients were randomized after FGG: PRF with butyl-cyanoacrylate (BC) adhesive (PRF group; n = 42), BC adhesive alone (BC group; n = 42), and sterile wet gauze compression (WG group; n = 41). Bleeding, pain, epithelialization, feeding habits, and sensation scores were recorded for different time points. Statistically significant differences were found for all parameters in favor of the PRF group (P = .0001). PRF may provide significant benefits for wound healing parameters and patients' postoperative course after palatal graft harvesting.