CYPRUS JOURNAL OF MEDICAL SCIENCES, cilt.5, ss.145-152, 2020 (ESCI İndekslerine Giren Dergi)
Makale / Tam Makale
CYPRUS JOURNAL OF MEDICAL SCIENCES
In this study, we aimed to determine the clinical value of the Hemoglobin and Albumin Levels and Lymphocyte and Platelet (HALP) score in predicting postoperative complications, lymph node positivity and prognosis in patients with gastric cancer undergoing curative surgical resection.
MATERIAL and METHODS
Patients who underwent total gastrectomy for gastric adenocarcinoma between 2015-2018 were included in the study. Two groups, Group1 (lowHALP) and Group2 (highHALP), were formed. Demographic and clinical characteristics and mean survival were compared. The value of HALP score in predicting lymph node positivity and postoperative complications was evaluated at the determined cut-off value.
Patients were divided into two groups according to the cut-off value of 14.98. Group 1 consisted of 20 patients and Group 2 consisted of 62 patients. The average age in Group 1 was higher than Group 2 (65vs57) (p=0.046). Female sex was higher in Group 2 than Group 1 (38.7%vs15%) (p=0.042). Total survival time was higher in Group 1 (41vs28) (p=0.02). We did not find HALP score as a risk factor for survival in multivariate analysis (HR=0.247, 95% CI=0.113-0.485, p=0.061). According to the cut-off value, if the HALP value was above 14.98, it was seen that ClavienDindo 2 and more complications developed with 84.09% sensitivity and 33.33% specificity. It is assumed that the person's lymph node is positive with a HALP value 9.14 and below, with sensitivity of 20.00% and specificity of 96.97%.
Our findings showed that HALP is closely related to clinicopathological features but it is not an independent prognostic factor for survival. Its value in predicting the risk of complication development and lymph node positivity is limited.
Keywords: Gastric cancer, HALP score postoperative complications, prognosis