Bakırköy Tıp Dergisi, vol.17, no.3, pp.203-208, 2021 (ESCI)
Objective: This study aimed to examine the demographic features, clinicopathological findings, follow-up results, and treatment methods of patients treated for phyllodes tumors of the breast in light of the literature. Methods: All patients with benign, borderline, or malignant phyllodes tumors admitted to our hospital between 2013 and 2020 were retrospectively analyzed. Results: The study included a total of 14 patients with phyllodes tumors of the breast on histopathological examinations, wherein 6 were benign (42.9%), 3 were borderline (21.4%), and 5 were malignant (35.7%). The mean age was similar in the groups (p=0.654). Tumors were more frequently located in the right breast; however, no difference was found between the groups in terms of laterality (p=0.514). The tumor diameter was significantly smaller in benign phyllodes (benign: 32 mm, borderline: 72 mm, and malignant: 80 mm, p=0.036). Benign phyllodes were more frequently breast imaging-reporting and data system (BI-RADS) 3 and malignant phyllodes were BI-RADS 5; however, the difference was not significant. A core needle biopsy was performed in eight patients as the most common biopsy method (57.1%). The most common surgical procedure was segmental mastectomy (71.4%). Re-excision was performed in three patients due to the surgical margin positivity or closeness. One patient received chemotherapy and radiotherapy (RT) and 4 patients only received RT. The mean follow-up time was 53.8±25.4 months (13-96 months). Local recurrences occurred in two patients during the follow-up. Distant metastases or deaths were not observed. Conclusion: Phyllodes tumors are rare, mixed-type breast tumors. Histopathological features and classification guide the management plan. Extensive analysis of phyllodes tumors is still lacking, and more studies are necessary to understand the behavior of this rare breast tumor.