Familial Takayasu arteritis in a mother and daughter: a report of two cases

DENİZ A., YILDIZ F., Aktas H., Berk G. I., ERKEN E., DEMİRTAŞ M.

HERZ, cilt.38, sa.1, ss.93-96, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1007/s00059-012-3653-6
  • Dergi Adı: HERZ
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.93-96
  • Çukurova Üniversitesi Adresli: Evet

Özet

Takayasu arteritis (TA) is a chronic granulomatous panarteritis, predominantly affecting the aorta and its main branches. Infections, genetic factors as suggested by familial clustering, and autoimmunity may play a role in its pathogenesis. In this report, we describe familial TA in a mother and daughter with diverse clinical manifestations. In addition to being a familial form of vasculitis, both of our cases demonstrated amyloidosis, chronic renal disease thought to be due to ischemic nephropathy, and hypertensive nephrosclerosis.