Effects of Intraperitoneally Administered Folic Acid on the Healing of Repaired Tibial Nerves in Rats

HARMA A., Sahin M. S., ZORLUDEMİR S.

JOURNAL OF RECONSTRUCTIVE MICROSURGERY, cilt.31, sa.3, ss.191-197, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 3
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1055/s-0034-1395414
  • Dergi Adı: JOURNAL OF RECONSTRUCTIVE MICROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.191-197
  • Anahtar Kelimeler: folic acid, peripheral nerve, nerve repair, regeneration, CENTRAL-NERVOUS-SYSTEM, TO-SIDE NEURORRHAPHY, AXONAL REGENERATION, FUNCTIONAL RECOVERY, HYALURONIC-ACID, DNA METHYLATION, SUPPLEMENTATION, FOLATE, ADULT
  • Çukurova Üniversitesi Adresli: Evet

Özet

Background Complete nerve regeneration and clinical healing remain a challenge despite considerable advances in the treatment of peripheral nerve injuries. To improve nerve regeneration, several experimental molecular procedures have been attempted. This study aimed to investigate the effects of folic acid on peripheral nerve healing after transection and end-to-end suture repair of the tibial nerve in rats.