Study for the Diagnostic Screening of Paroxysmal Nocturnal Hemoglobinuria in Older Patients with Unexplained Anemia and/or Cytopenia

Ozdemir, Zehra; İLHAN, OSMAN; Ozet, Gulsum; Falay, Mesude; Yenerel, Mustafa; Tuglular, Tulin; Turgut, Mehmet; GÜVENÇ, BİROL; ÜNAL, ALİ; Ayyildiz, Orhan; ANDIÇ, NESLİHAN; Hacihanefioglu, Abdullah; ŞAHİN, FAHRİ; ŞENCAN, MEHMET; ALİ, RIDVAN; ÖZSAN, GÜNER; Yildirim, Rahsan; TİFTİK, EYÜP; TOMBAK, ANIL; SALİM, OZAN; KAYA, EMİN; Akay, Olga; Okan, Vahap; PEHLİVAN, MUSTAFA; SAYDAM, GÜRAY

doi:10.7754/clin.lab.2020.191218

Study for the Diagnostic Screening of Paroxysmal Nocturnal Hemoglobinuria in Older Patients with Unexplained Anemia and/or Cytopenia

Ozdemir Z. N., İLHAN O., Ozet G., Falay M., Yenerel M., Tuglular T., ...Daha Fazla

CLINICAL LABORATORY, cilt.66, sa.9, ss.1709-1715, 2020 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 66 Sayı: 9
Basım Tarihi: 2020
Doi Numarası: 10.7754/clin.lab.2020.191218
Dergi Adı: CLINICAL LABORATORY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
Sayfa Sayıları: ss.1709-1715
Çukurova Üniversitesi Adresli: Evet

Özet

Background: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired hematopoietic stem cell disease that may lead to weakness and death of patients, if unrecognized and untreated. Although consensus guidelines were reviewed recently for the diagnostic screening of PNH with multi-parameter flow cytometry (FCM), until now, no study has investigated the efficiency of such clinical indications in older patients.