Comparative analysis of selected cagPAI genes and different vacA genotypes in Iranian and Turkish H. pylori-positive patients suffering from gastric adenocarcinoma and active chronic gastritis

BAHADORI A., HOSSEIN SOMI M., DORAN F., EFTEKHARSADAT A., KIZILYILDIRIM S., ESMAEILLOU M., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.47, sa.3, ss.916-922, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.3906/sag-1606-116
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.916-922
  • Çukurova Üniversitesi Adresli: Evet

Özet

Background/aim: Helicobacter pylori is a pathogen that colonizes a majority of the world's population. Genetic diversity within the virulence genes of bacteria such as cagPAI and vacA may have a modified effect on the pathogenic potential of the bacteria. This study aimed to investigate which genes can be suggested as potentially related virulence factors for H. pylori-associated active chronic gastritis and stomach adenocarcinoma in the northwest of Iran and south of Turkey.