The Effects of Androgens on Cardiometabolic Syndrome: Current Therapeutic Concepts


Kirlangic O. F., Yilmaz-Oral D., Kaya-Sezginer E., Toktanis G., Tezgelen A. S., Sen E., ...More

SEXUAL MEDICINE, vol.8, no.2, pp.132-155, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 8 Issue: 2
  • Publication Date: 2020
  • Doi Number: 10.1016/j.esxm.2020.02.006
  • Journal Name: SEXUAL MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, Directory of Open Access Journals
  • Page Numbers: pp.132-155
  • Çukurova University Affiliated: Yes

Abstract

Introduction: Cardiometabolic syndrome (CMS), as a bunch of metabolic disorders mainly characterized by type 2 diabetes mellitus (T2DM), hypertension, atherosclerosis, central adiposity, and abdominal obesity triggering androgen deficiency, is one of the most critical threats to men. Although many significant preclinical and clinical findings explain CMS, new approaches toward common pathophysiological mechanisms and reasonable therapeutic targets are lacking.