Akademik Veri Yönetim Sistemi
TROPICAL ANIMAL HEALTH AND PRODUCTION, cilt.44, sa.3, ss.453-457, 2012 (SCI-Expanded)
The aim of this study was to examine the coagulation profile in peste des petits ruminant (PPR) in kids. Five kids from a group of 150 animals (72 goats and 78 kids) were brought to the Veterinary Medical Teaching Hospital from a farm in Burdur province (Turkey) with nasal and ocular discharges and diarrhea. Fifteen goats and 41 kids had died due to diarrhea and three kids were presented to the Department of Pathology for diagnosis. Blood samples were taken from 12 ill animals (infected group) for haematological and biochemical analysis. In addition, five healthy kids were examined from another healthy flock (control group). Leukocyte and lymphocyte numbers of infected group showed significant declinations in comparison to control group (a parts per thousand currency sign0.001). Haemorrhages in all organs of digestive system and small haemorrhagic areas in liver were caused to decrease in erythrocyte and haematocrit values (p a parts per thousand currency signaEuro parts per thousand 0.001) in infected group. Concentrations of blood urea nitrogen (BUN) (p a parts per thousand currency signaEuro parts per thousand 0.01) and creatinine (p a parts per thousand currency signaEuro parts per thousand 0.001) in infected group were significantly higher than control group. Compared to control group, significant increases were determined in serum concentrations of alkaline phosphatase (ALP) (p a parts per thousand currency signaEuro parts per thousand 0.01), aspartate aminotransferase (AST) (p a parts per thousand currency signaEuro parts per thousand 0.001) and alanine aminotransferase (ALT) (p a parts per thousand currency signaEuro parts per thousand 0.001) in the infected group. No significant differences were observed between the infected and control groups for serum gamma glutamyl-transferase (GGT) concentration value. In our study, thrombocytopenia (p a parts per thousand currency signaEuro parts per thousand 0.001) together with prolonged activated partial thromboplastin time (APTT; p a parts per thousand currency signaEuro parts per thousand 0.01) and prothrombin time (PT; p a parts per thousand currency signaEuro parts per thousand 0.001) may show that disseminated intravascular coagulopathy which can occur in kids with PPR.