The effects of various rootstocks on yield, yield efficiency, vegetative growth and fruit quality of Santa Teresa lemon variety were evaluated under Adana ecological conditions during 2004 and 2005. Canopy volume was the lowest for trees on Carrizo citrange, followed by Troyer citrange and Citrus ampullacea. Total cumulative yield over two years of production was highest on C. obovoidea, followed by that on Citrus sulcata. On the other hand, the trees on C. citrange were the most efficient in yield per cubic meter of canopy volume (CV) and trunk cross-sectional area (TCSA) due to its small TCSA and CV. The largest fruit size was obtained from the trees on C. sulcata, Taiwanica, C. ampullacea, followed by sour orange and Citrus obovoidea. The highest total acid content of fruits was found with sour orange and T. citrange, followed by C. obovoidea. When all the results are considered, it can be concluded that C. obovoidea was more promising rootstock for Santa Teresa lemon in Cukurova Region.