HealthCare-associated Infections in a Neonatal Intensive Care Unit in Turkey in 2008: Incidence and Risk Factors, A Prospective Study

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Yapicioglu H. , OZCAN K., Sertdemir Y. , MUTLU B., SATAR M. , NARLI N. , ...Daha Fazla

JOURNAL OF TROPICAL PEDIATRICS, cilt.57, sa.3, ss.157-164, 2011 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 57 Konu: 3
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1093/tropej/fmq060
  • Sayfa Sayıları: ss.157-164


In this study, we have prospectively recorded healthcare-associated infections (HAIs) in NICU and found incidence density as 18 infections per 1000 patient days. Of the infections, 51.3% was bacteriemia (BSI), and 45.1% was ventilator-associated pneumonia (VAP). Gram-negative microorganisms were predominant in VAP and Staphylococcus epidermidis was the leading microorganism (53.0% of BSIs) in BSIs. Multivariate logistic regression analysis showed the importance of hood O(2) use in days (RR: 1.3) and total parenteral nutrition use in days (RR: 1.09) for BSIs. Umbilical arterial catheterization in days (RR: 1.94), ventilator use in days (RR: 1.05), chest tube (RR: 12.55), orogastric feeding (RR: 3.32) and total parenteral nutrition in days (RR: 1.05) were found to be significantly associated with VAP. In conclusion, incidence density in our unit is high and Gram-negative rods are predominant similar to developing countries. These results strongly suggest improving measures of prevention and control of HAIs in the unit.