Antioxidant, Antimicrobial, and Insecticidal Properties of a Chemically Characterized Essential Oil from the Leaves of Dittrichia viscosa L.

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Mssillou I., Agour A., Allali A., Saghrouchni H., Bourhia M., El Moussaoui A., ...More

MOLECULES, vol.27, no.7, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 7
  • Publication Date: 2022
  • Doi Number: 10.3390/molecules27072282
  • Journal Name: MOLECULES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Communication Abstracts, EMBASE, Food Science & Technology Abstracts, MEDLINE, Metadex, Veterinary Science Database, Directory of Open Access Journals, Civil Engineering Abstracts
  • Keywords: antimicrobial, C, maculatus, D, viscosa, free radical, GC-MS, insecticidal characteristic, medicinal plants, volatile compounds, CALLOSOBRUCHUS-MACULATUS, INULA-VISCOSA, MEDICINAL-PLANTS, COLEOPTERA-CHRYSOMELIDAE, STORED CHICKPEA, BORNYL ACETATE, PEST STATUS, EXTRACT, ANTIBACTERIAL, CHINENSIS
  • Çukurova University Affiliated: Yes

Abstract

Since some synthetic insecticides cause damage to human health, compounds in plants can be viable alternatives to conventional synthetic pesticides. Dittrichia viscosa L. is a perennial Mediterranean plant known to possess biological activities, including insecticidal properties. The chemical composition of an essential oil (EOD) from D. viscosa, as well as its antioxidant, antimicrobial, and insecticidal effects on the cowpea weevil (Callosobruchus maculatus) were determined. Forty-one volatile compounds were identified in EOD, which accounted for 97.5% of its constituents. Bornyl acetate (41%) was a major compound, followed by borneol (9.3%), alpha-amorphene (6.6%), and caryophyllene oxide (5.7%). EOD exhibited significant antioxidant activity in all tests performed, with an IC50 of 1.30 +/- 0.05 mg/mL in the DPPH test and an EC50 equal to 36.0 +/- 2.5 mg/mL in the FRAP assay. In the phosphor-molybdenum test, EOD results ranged from 39.81 +/- 0.7 to 192.1 +/- 0.8 mg AAE/g E. EOD was active on E. coli (9.5 +/- 0.5 mm), S. aureus (31.0 +/- 1.5 mm), C. albicans (20.4 +/- 0.5 mm), and S. cerevisiae (28.0 +/- 1.0 mm), with MICs ranging from 0.1 mg/mL to 3.3 mg/mL. We found that 1 mu L of EOD caused 97.5 +/- 5.0% insect mortality after 96 h in the inhalation test and 60.0 +/- 8.3% in the ingestion assay. The median lethal concentration (LC50) was 7.8 +/- 0.3 mu L EO/L, while the effective concentration in the ingestion test (LC50) was 15.0 +/- 2.1 mu L EO/L. We found that 20 mu L of EOD caused a reduction of more than 91% of C. maculatus laid eggs.