Is aortic knob width a novel predictor of mortality in hemodialysis patients?


KAYA B., METE B., BALAL M., SEYREK N., KARAYAYLALI İ.

European Review for Medical and Pharmacological Sciences, vol.28, no.7, pp.2805-2816, 2024 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 7
  • Publication Date: 2024
  • Doi Number: 10.26355/eurrev_202404_35909
  • Journal Name: European Review for Medical and Pharmacological Sciences
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals
  • Page Numbers: pp.2805-2816
  • Keywords: Aortic knob width, Atherosclerosis, Chronic renal disease, Hemodialysis, Mortality
  • Çukurova University Affiliated: Yes

Abstract

Abstract. – OBJECTIVE: Identifying reliable PATIENTS AND METHODS: The study in-predictors of mortality in end-stage renal dis- cluded data collected between 2007 and 2022 ease patients is crucial for patient outcomes. from 103 patients aged between 18 and 85 who Aortic knob width is a radiographic parameter had been undergoing hemodialysis treatment used to assess cardiovascular diseases and ath- for at least one year. Patients were divided into erosclerosis. This study investigated the associ- two groups: survivors and deceased. The aortic ation between aortic knob width and mortality in knob width was measured using a posterior-an-hemodialysis patients. terior chest radiograph after midweek hemodial- ysis. The relationship between aortic knob width and mortality was investigated. RESULTS: Deceased patients had significantly larger aortic knob widths compared with survivors. The deceased group’s hemodialysis (HD) duration was shorter, median age was older, Kt/V, hemoglobin, and albumin levels were lower, and the frequency of patients with hypertension, diabetes, and aortic wall calcification was higher. Aortic knob width greater than 37.98 mm was identified as a predictor of mortality in hemodialysis patients. Survival rates for aortic knob width <37.98 mm are 98.1% for 1 year and 64.9% for 15 years. For aortic knob width larger than 37.98 mm, survival rates are 88% for three years, 68% for five years, 45.2% for ten years, and 25% for fifteen years. The most important risk factors for increased aortic knob width were age, male sex, aortic calcification, and hypertension. CONCLUSIONS: Age, male gender, aortic calcification, and hypertension are the primary risk factors for increased aortic knob width in hemodialysis patients. Aortic knob width greater than 37.98 mm, which can be measured simply and rapidly using posterior-anterior chest radiography, may be a predictor of mortality.