Tramadol Reverses the Effects of Neuropathic Pain on Oocyte Maturation and Copulation Ratio in Mice


DAĞILGAN S., ERDOĞAN Ş. , AKSU F.

EURASIAN JOURNAL OF MEDICINE, cilt.50, ss.182-186, 2018 (ESCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 50 Konu: 3
  • Basım Tarihi: 2018
  • Doi Numarası: 10.5152/eurasianjmed.2018.17199
  • Dergi Adı: EURASIAN JOURNAL OF MEDICINE
  • Sayfa Sayıları: ss.182-186

Özet

Objective: Neuropathic pain (NP) is an inescapable stressor that significantly affects both the nervous and endocrine system functions. In this study, we investigated the effect of NP on female reproductive function using the number of oocytes as an index as well as the copulation rates of female mice, with and without males. We also examined whether NP symptoms stopped after injecting tramadol, an opioid analgesic.